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Technická 5
166 28 Prague 6 – Dejvice
IČO: 60461373 / VAT: CZ60461373

Czech Post certified digital mail code: sp4j9ch

Copyright: UCT Prague 2015
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originál

                                                                                                                   originál     originál     originál

http://www.oppk.cz

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Project name

Prague University Analytical Centre for Health, Food Safety and Environmental Protection – II

Registration number

CZ.2.16/3.1.00/21537

Fund

European Regional Development Fund

Program

Operational Programme Prague – Competitiveness

Support area 3.1- Development of innovation environment and partnership between the research and development base and practice

Project Focus

Basic research

Applicant

University of Chemistry and Technology Prague

Partners

3rd Faculty of Medicine of Charles University

National Institute of Public Health 

Institute of Microbiology ASCR, v.v.i.

Institute of Experimental Medicine ASCR, v.v.i.

 

Public funding total: 49,566,891 CZK
ERDF contribution (85%): 42,131,857 CZK
Period of realization: 1. 1. 2014 - 31. 7. 2015
 
Description

The realized project builds on the project PVAC I in order to create a unique, integrated workplace, dealing with basic research in the field of forensic analysis, authenticity of food and pharmaceutical preparations, genomics and proteomics, whose main thesis is to increase the quality of nonmaterial aspects of life of inhabitants of Prague, Czech Republic, European Union.
The project aims to create a center which comprises cutting edge analytical instruments and erudite experts in the field of analytical, medical, environmental and food chemistry at the platform of top university workplace, which is a traditional source of inspiration, information, and an indicator of developments in the field of basic research for related application areas and commercial sphere.

originál     originál     originál

Prague & EU: We Invest in Your Future

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originál

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Project Manager

Prof. Jan Poustka, MSc, PhD

Project Secretary

Prof. Jana Hajšlová, MSc, PhD

 

 

Forensic Analysis Centre

Guarantor for the field of food authenticity

Prof. Jana Hajšlová, MSc, PhD

Guarantor for the field of medicine authenticity

Prof. Štěpán Urban, MSc, PhD

 

Genomics and Proteomics Centre

Guarantor

Assoc.Prof. David Sýkora, MSc, PhD

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2015-2016

Research papers

1) Kubešová, A., Tejkalová, H., Syslová, K., Vondroušová, J., Tyls, F., Fujáková, M., Páleníček, T., Horáček, J., Kačer, P.: Biochemical, histopathological and morphological profiling of a rat model of early immune stimulation: relation to psychopatology, PLoS One (2015) 10(1): 1-16. DOI:10.1371/journal.pone.0115439.

2) Rudá-Kučerová, J., Amchová, P., Havlíčková, T., Jeřábek, P., Kačer, P. Syslová, K., Šulcová, A., Šustková-Fišerová, M.: Reward related neurotransmitter changes in a model of depression: An in vivo microdialysis study, The world journal of biological psychiatry: the official journal of the World Federation of Societies of Biological Psychiatry (2015) 16(7): 521-35.

3) Bunganič, B., Šťovíčková, L., Tatarkovič, M., Kocourková, L., Suchánek, Š., Frič P., Setnička, V., Zavoral, M.: Molekulárně spektroskopická analýza krevní plazmy – cesta k diagnostice karcinomu pankreatu?, Gastroenterologie a Hepatologie, (2015) 69 (6): 518–524, DOI: 10.14735/amgh2015518.

Patents

1) Kysilka V., Mengler J., Havlovič K., Kačer P., Červený L., Platinum (IV) complex with increased antitumor efficacy" PCT/EP2014/068672, publikováno: 10.3.2016, WIPO WO/2016/034214)

 2) Loužilová T., Syslová K., Svoboda J., Mikoška M., Kačer P., Červený L., Maixner J., Pažout R., Rozpustný platnatý komplex s pyridinkarboxamidinovým ligandem a způsob jeho přípravy“, PV2014-916. Publikováno: 29.6.2016, VĚSTNÍK ÚŘADU PRŮMYSLOVÉHO VLASTNICTVÍ

2016-2017

Research papers

4) Neprašová, M., Maixnerová, D., Novák, J., Reily, C., Julian, B.A., Boroň, J.,  Novotný, P.,  Suchánek, M., Tesař, V., Kačer, P.: Toward Noninvasive Diagnosis of IgA Nephropathy: A Pilot Urinary Metabolomic and Proteomic Study, Hindawi Publishing Corporation Disease Markers, Volume 2016, Article ID 3650909, http://dx.doi.org/10.1155/2016/3650909.

5) Kocourková, L., Ullrichová, P., Habartová, L., Čujová, S., Čerovský, V., Urbanová, M., Setnička, V.: Vibrational and electronic circular dichroism as powerful tools for the conformational analysis of cationic antimicrobial peptides, Monatshefte für Chemie (2016) 147 (8): 1439-1445, DOI: 10.1007/s00706-016-1807-6.

6) Righetti, L., Rubert, J., Galaverna, G., Folloni, S., Ranieri, R., Stránská-Zachariášová, M., Hajšlová, J., Dall´Asta, C.: Characterization and discrimination of ancient grains: A metabolomics approach, International Journal of Molecular Sciences (2016) 17: 1217-1230, DOI: 10.3390/ijms17081217.

7) Stránská-Zachariášová, M., Kaštánek, P., Džuman, Z., Rubert, J., Godula, M., Hajšlová, J.: Bioprospecting of microalgae: Proper extraction followed by high performance liquid chromatographic–high resolution mass spectrometric fingerprinting as key tools for successful metabolom characterization, Journal of chromatography B - analytical technologies in the biomedical and life sciences (2016) 1015–1016: 22–33, DOI:10.1016/j.jchromb.2016.01.050.

8) Jírů, M., Džuman, Z., Stránská, M., Hajšlová, J.: Metodika hmotnostně-spektrometrického screeningu nedeklarovaných syntetických inhibitorů fosfodiesterázy typu 5 (PDE-5) a jejich analogů v herbálních doplňcích stravy, UPLATNĚNÁ CERTIFIKOVANÁ METODIKA, Vysoká škola chemicko-technologická v Praze, Ústav analýzy potravin a výživy, FPBT Technická 3, 166 28 Praha – 6 Dejvice, 2016, ISBN 978-80-7080-981-5.

9) Schusterová, D., Suchanová, M., Tomaniová, M., Kocourek, V., Hajšlová, J.: Cílová analýza pesticidních látek a jejich metabolitů v rostlinných materiálech z ekologické produkce, UPLATNĚNÁ CERTIFIKOVANÁ METODIKA, Vysoká škola chemicko-technologická v Praze, Ústav analýzy potravin a výživy, FPBT Technická 3, 166 28 Praha – 6 Dejvice, 2016, ISBN 978-80-7080-980-8.

10) Hajšlová, J., Hrbek, V., Rektorisová, M., Kocourek, V.: Stanovení charakteristických g-dipeptidů S-alk(en)ylcysteinsulfoxidů s kyselinou L-glutamovou a jejich redukovaných forem v česneku a cibuli, UPLATNĚNÁ CERTIFIKOVANÁ METODIKA, Vysoká škola chemicko-technologická v Praze, Ústav analýzy potravin a výživy, FPBT Technická 3, 166 28 Praha – 6 Dejvice, 2016, ISBN 978-80-7080-976-1.

11) Pažout, R., Maixner J., Pecháček, J., Vilhanová, B., Kačer, P.: Synthesis and characterization of two new chiral Kemp’s acid derivatives: structures fixed by a peculiar system of N–H···O, C–H···O and C–H···N hydrogen bonds, Zeitschrift fur Kristallographie - Crystalline Materials (2016) 231 (9): 531-539, DOI: 10.1515/zkri-2016-1962.

12) Kocourková, L., Novotná, P., Čujová, S., Čerovský, V., Urbanová, M., Setnička, V.: Conformational study of melectin and antapin antimicrobial peptides in model membrane environments, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (2017) 170: 247–255.

13) Berthiller, F., Brera, C., Iha, M.H., Krska, R., Lattanzio, V.M.T., MacDonald, S., Malone R.J., Maragos, C., Solfrizzo, M., Stránská-Zachariášová, M., Stroka J., Tittlemier, S.A.: Developments in Mycotoxin Analysis: An Update for 2015-2016, World Mycotoxin Journal (2017) 10 (1): 5-29, DOI: 10.3920/WMJ2016.2138.

14) Hůrková, K.,  Rubert, J., Stránská-Zachariášová, M.,  Hajšlová, J.: Strategies to Document Adulteration of Food Supplement Based on Sea Buckthorn Oil: a Case Study,  Food Analytical Methods (2017) 10: 1317–1327, DOI 10.1007/s12161-016-0674-4.

15) Rubert, J., Righetti, L., Stránská-Zachariášová M., Džuman, Z., Chrpová, J., Dall’Asta, C., Hajšlová, J.: Untargeted metabolomics based on UHPLC-HRMS merged with chemometrics: A predictable tool for an early detection of mycotoxins, Food Chemistry (2017) 224: 423–431.

16) Urbancová, K., Lanková, D., Rossner, P., Rossnerová, A., Švecová, V., Tomaniová, M., Velemínský, M. Jr., Šrám, R. J., Hajšlová, J., Pulkrabová J.: Evaluation of 11 polycyclic aromatic hydrocarbon metabolites in urine of Czech mothers and newborns, Science of the Total Environment (2017) 577: 212–219.

17) Stránská-Zachariášová, M., Kurniatanty, I., Gbelcová, H., Jírů, M., Rubert J., Nindhia T.G.T., D’Acunto, C.W., Sumarsono, S.H., Tan, M.I., Hajšlová, J., Ruml T.: Bioprospecting of Turbinaria macroalgae as a potential source of health protective compounds,  Chemistry & Biodiversity (2017) 14, e1600192 DOI: 10.1002/cbdv.201600192.

18) Kosek, V., Stránská, M., Fenclová, M., Ruml, T., Vítek, L., Hajšlová, J.: High resolution mass spectrometry based method applicable for a wide range of 3-hydroxy-3-methyl-glutaryl-coenzyme A reduktase inhibitors in blood serum including intermediates and products of the cholesterol biosynthetic pathway, Journal of Chromatography A (2017) 1489: 86–94.

19) Vytejčková, S., Vápenka, L., Hradecký, J., Dobiáš, J., Hajšlová, J., Loriot, C., Vannini, L., Poustka, J.: Testing of polybutylene succinate based films for poultry meat packaging, Polymer Testing (2017) 60: 357-364.

20)  Riedlová, K., Nekardová, M., Kačer, P., Syslová, K., Vazdar, M., Jungwirth, P., Kudová, E., Cwiklik, L.: Distributions of therapeutically promising neurosteroids in cellular membranes, Chemistry and Physics of Lipids  (2017) 203: 78–86.

21) Matuška, O., Kindl, M., Kačer, P.: Asymmetric transfer hydrogenation of C=O and C=N bonds catalyzed by [Ru(η6arene) (diamine)] complexes: a multilateral study, Research Article in: Ravanchi, M. T., New Advances in Hydrogenation Processes - Fundamentals and Applications ISBN 978-953-51-2869-4l, 2017.

22) Kindl, M., Matuška, O., M., Kačer, P.: Organometallics; Exploration Tool for Surface Phenomena in Heterogeneous Catalysis, Research Article in: Ravanchi, M. T., New Advances in Hydrogenation Processes - Fundamentals and Applications ISBN 978-953-51-2869-4l, 2017.

23) Socas-Rodríguez, B., Lanková, D., Urbancová, K., Krtková, V. Hernández-Borges, J., Rodríguez-Delgado, M. A., Pulkrabová, J., Hajšlová, J.: Multiclass analytical method for the determination of natural/synthetic steroid hormones, phytoestrogens, and mycoestrogens in milk and yogurt, Analytical and Bioanalytical Chemistry (2017) 409: 4467-4477.

24) Stupák, M., Kocourek, V., Kolouchová, I., Hajšlová, J.: Rapid approach for the determination of alcoholic strength and overall quality check of various spirit drinks and wines using GC-MS, Food Control (2017) 80: 307-313.

25) Fagan, P., Kocourková, L., Tatarkovič, M., Králík, F., Kuchař, M., Setnička, V., Bouř, P.: Cocaine Hydrochloride Structure in Solution Revealed by Three Chiroptical Methods, ChemPhysChem (2017) 18(16): 2258-2265, doi: 10.1002/cphc.201700452.

26) Fagan P., Králík F., Kuchař M., Setnička V.: Studium struktury heroinu v roztoku spektroskopickými metodami, Czech Chem. Soc. Symp. Ser., 2017, 15(2), pp. 64-67, ISSN 2336-7202 (print), ISSN 2336-7210 (on-line).

27) Fagan P., Králík F., Kuchař M., Bouř P., Setnička V.: Chiroptická spektroskopie v identifikaci a strukturní analýze heroinu a kokainu, recenzovaný Sborník sdělení z 3. ročníku mezinárodní vědecké konference Trestně právní a kriminalistické aspekty dokazování (Straus J., Bruna E., Eds.), Praha, 9. 3. 2017, p. 36-49, ISBN 978-80-7408-153-8.

28) Kozánková J., Králík F., Kuchař M., Setnička V.: Možnosti identifikace padělků přípravku Viagra®, recenzovaný Sborník sdělení z 3. ročníku mezinárodní vědecké konference Trestně právní a kriminalistické aspekty dokazování (Straus J., Bruna E., Eds.), Praha, 9. 3. 2017, p. 126-139, ISBN 978-80-7408-153-8.

29) Spálovská D., Králík F., Kuchař M., Setnička V.: Studium nových syntetických drog v roztoku metodami vibrační spektroskopie, recenzovaný Sborník sdělení z 3. ročníku mezinárodní vědecké konference Trestně právní a kriminalistické aspekty dokazování (Straus J., Bruna E., Eds.), Praha, 9. 3. 2017, p. 300-310, ISBN 978-80-7408-153-8.

30) Králík F., Jurásek B., Kuchař M., Setnička V.: Využití metod chiroptické spektroskopie pro studium psychoaktivních látek, recenzovaný Sborník sdělení z 3. ročníku mezinárodní vědecké konference Trestně právní a kriminalistické aspekty dokazování (Straus J., Bruna E., Eds.), Praha, 9. 3. 2017, p. 140-150, ISBN 978-80-7408-153-8.

31) Zajíčková L., Králík F., Kuchař M., Setnička V.: Vibračně spektroskopická analýza přípravků obsahujících anabolické steroidy, recenzovaný Sborník sdělení z 3. ročníku mezinárodní vědecké konference Trestně právní a kriminalistické aspekty dokazování (Straus J., Bruna E., Eds.), Praha, 9. 3. 2017, p. 408-419, ISBN 978-80-7408-153-8.

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AUTHENT-NET - Food Authenticity Research Network 

(www.authent-net.eu)

The project is aimed at facilitating of the sustainable co-operation between national and international research funding bodies in the area of ​​food authenticity. The aim is to improve competitiveness within the food chain and consumer confidence through better coordinated and cost-effective R & D activities.

EC, H2020 (H2020-SFS-2015-1-696371), Project Solution Duration 1.4.2016 - 31.3.2018

Principal Investigator for ICT Prague: Prof. Jana Hajšlová, MSc, PhD

Collaborating Entity: Project Coordinator - Fera Science Ltd, York, UK

Type of collaboration: Coordinated Supported Action

Results: Contribution to the Food Authenticity Research Hub (FARNH) database, eg. in the form of the National Status Report, organization of workshops, newsletters, etc.

 

MultiCoop - Multidisciplinary approach to strengthen cooperation and establish novel platform for comprehensive assessment of food and feed safety  

(www.multicoop.eu)

The project is aimed at enhancing of the cooperation and support for the emergence of new projects and human resources development for the participating partners (ICT Prague, QUB and BOKU) through the development of excellence and expertise in the area of ​​comprehensive food safety and feed safety assessment.

EC, H2020 (H2020-TWINN-2015-Twinning, 692195), Project Solution Duration 1.1.2016 - 31.12.2018

Principal Investigator for ICT Prague and Project Coordinator: Prof. Jana Hajšlová, MSc, PhD

Collaborating entity: The University of Natural Resources and Life Sciences, Vienna (BOKU), Austria; Queen's University Belfast, Belfast, UK

Type of collaboration: Twinning

Results: Several training sessions were held in 2016, a number of dissemination activities such as presentations at international conferences etc.

Scientific publications:

Stranska-Zachariasova, M., Kastanek, P., Dzuman, Z., Rubert, J., Godula, M., Hajslova, J .: Bioprospecting of microalgae: Proper extraction followed by high performance liquid chromatography-high resolution mass spectrometric fingerprinting as key tools for successful metabolom Characterization. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN BIOMEDICAL AND LIFE SCIENCES (2016) 1015-1016: 22-33, (DOI: 10.1016 / j.chchromb.2016.01.050). IF 2,687

Stranska-Zachariasova, M., Kurniatants, I., Gbelcova, H., Jiru, M., Rubert, J., Nindhia, T.G.T., D'Acunto, C.W., Sumarsono, S.H., Tan, M.I., Hajslova, J., Ruml, T .: Bioprospecting of Turbinaria macroalgae as a potential Source of health protective compounds. Chemistry & Biodiversity, accepted. (DOI: 10.1002 / cbdv.201600192). IF 1.444


Microalgae as perspective sources of omega-3 unsaturated fatty acids and their incorporation into the human food chain

TAČR - TA03011027 (2013-2016)

Partner from Practice:
Ecofuel Laboratories, s.r.o.

 

Characterization and selection of C. sativa for both food and non-food uses using biotechnological procedures and high-capacity methods

TAČR - TA04010331 (2014-2017)

Partner from practice: CANNABIS Pharma, s.r.o.

  

New comprehensive strategy for determining of the biological effects of mixtures of chemicals found in food and food supplements

GAČR (16-06008S), 2016 - 2018

Principal Investigator for ICT Prague and Project Coordinator:
Assoc.Prof. Milena Stranska, PhD

Collaborating entity: Charles University in Prague, 1st Faculty of Medicine

Type of collaboration: Scientific research

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Project Manager

Prof. Jan Poustka, MSc, PhD

VŠCHT Budova B, místnost B138
Technická 3, 166 28 Praha 6 – Dejvice

Tel.: 220 443 218; e-mail: Jan.Poustka@vscht.cz

 

Project Secretary

Assoc.Prof. Petr Kačer, PhD

VŠCHT Budova A, místnost A84
Technická 5, 166 28 Praha 6 – Dejvice

Tel.: 220 444 158; e-mail: Petr.Kacer@vscht.cz

 

Forensic Analysis Centre

Guarantor for the field of food authenticity

Prof. Jana Hajšlová, MSc, PhD

VŠCHT Budova B, místnost B137
Technická 3, 166 28 Praha 6 – Dejvice

Tel.: 220 443 185; e-mail: Jana.Hajslova@vscht.cz

Guarantor for the field of medicine authenticity

Prof. Štěpán Urban, MSc, PhD

VŠCHT Budova A, místnost A231
Technická 5, 166 28 Praha 6 – Dejvice

Tel.: 220 444 267; e-mail: Stepan.Urban@vscht.cz

 

Genomics and proteomics Centre

Guarantor

Assoc.Prof. Petr Kačer, MSc, PhD

VŠCHT Budova A, místnost A84
Technická 5, 166 28 Praha 6 – Dejvice

Tel.: 220 444 158; e-mail: Petr.Kacer@vscht.cz

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AUTHENT-NET - Food Authenticity Research Network 

(www.authent-net.eu)

The project is aimed at facilitating of the sustainable co-operation between national and international research funding bodies in the area of ​​food authenticity. The aim is to improve competitiveness within the food chain and consumer confidence through better coordinated and cost-effective R & D activities.

EC, H2020 (H2020-SFS-2015-1-696371), Project Solution Duration 1.4.2016 - 31.3.2018

Principal Investigator for ICT Prague: Prof. Jana Hajšlová, MSc, PhD

Collaborating Entity: Project Coordinator - Fera Science Ltd, York, UK

Type of collaboration: Coordinated Supported Action

Results: Contribution to the Food Authenticity Research Hub (FARNH) database, eg. in the form of the National Status Report, organization of workshops, newsletters, etc.

 

MultiCoop - Multidisciplinary approach to strengthen cooperation and establish novel platform for comprehensive assessment of food and feed safety  

(www.multicoop.eu)

The project is aimed at enhancing of the cooperation and support for the emergence of new projects and human resources development for the participating partners (ICT Prague, QUB and BOKU) through the development of excellence and expertise in the area of ​​comprehensive food safety and feed safety assessment.

EC, H2020 (H2020-TWINN-2015-Twinning, 692195), Project Solution Duration 1.1.2016 - 31.12.2018

Principal Investigator for ICT Prague and Project Coordinator: Prof. Jana Hajšlová, MSc, PhD

Collaborating entity: The University of Natural Resources and Life Sciences, Vienna (BOKU), Austria; Queen's University Belfast, Belfast, UK

Type of collaboration: Twinning

Results: Several training sessions were held in 2016, a number of dissemination activities such as presentations at international conferences etc.

Scientific publications:

Stranska-Zachariasova, M., Kastanek, P., Dzuman, Z., Rubert, J., Godula, M., Hajslova, J .: Bioprospecting of microalgae: Proper extraction followed by high performance liquid chromatography-high resolution mass spectrometric fingerprinting as key tools for successful metabolom Characterization. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN BIOMEDICAL AND LIFE SCIENCES (2016) 1015-1016: 22-33, (DOI: 10.1016 / j.chchromb.2016.01.050). IF 2,687

Stranska-Zachariasova, M., Kurniatants, I., Gbelcova, H., Jiru, M., Rubert, J., Nindhia, T.G.T., D'Acunto, C.W., Sumarsono, S.H., Tan, M.I., Hajslova, J., Ruml, T .: Bioprospecting of Turbinaria macroalgae as a potential Source of health protective compounds. Chemistry & Biodiversity, accepted. (DOI: 10.1002 / cbdv.201600192). IF 1.444


Microalgae as perspective sources of omega-3 unsaturated fatty acids and their incorporation into the human food chain

TAČR - TA03011027 (2013-2016)

Partner from Practice:
Ecofuel Laboratories, s.r.o.

 

Characterization and selection of C. sativa for both food and non-food uses using biotechnological procedures and high-capacity methods

TAČR - TA04010331 (2014-2017)

Partner from practice: CANNABIS Pharma, s.r.o.

  

New comprehensive strategy for determining of the biological effects of mixtures of chemicals found in food and food supplements

GAČR (16-06008S), 2016 - 2018

Principal Investigator for ICT Prague and Project Coordinator:
Assoc.Prof. Milena Stranska, PhD

Collaborating entity: Charles University in Prague, 1st Faculty of Medicine

Type of collaboration: Scientific research

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UCT Prague
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Copyright: UCT Prague 2015
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